SCHEMBL11264523

SCHEMBL11264523

OC(Cc1ccc(Cl)cc1Cl)(Cn1ccnc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.49
CYP11B2 P19099 1/20 0.49
OGG1 O15527 1/20 0.47
PTGS2 P35354 3/20 0.45
ADRA2C P18825 2/20 0.44
CYP2C9 P11712 4/20 0.44
IDO1 P14902 3/20 0.44
PGR P06401 2/20 0.44
CHRM2 P08172 2/20 0.44
CYP3A4 P08684 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
CYP2D6 P10635 2/20 0.44
CHRM1 P11229 2/20 0.44
ADRB3 P13945 2/20 0.44
ADRA2B P18089 2/20 0.44
CHRM3 P20309 2/20 0.44
TACR2 P21452 2/20 0.44
DRD1 P21728 2/20 0.44
ACHE P22303 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10813164 0.93 CYP19A1 (0.49) CYP11B1CYP11B2OGG1PTGS2ADRA2C
SCHEMBL11264045 0.93 OGG1 (0.49) CYP11B1CYP11B2OGG1PTGS2ADRA2C
Nitric Acid SCHEMBL11269538 0.93 CYP3A4 (0.52) CYP11B1CYP11B2OGG1PTGS2ADRA2C
Hydrochloric Acid SCHEMBL11266440 0.92 OGG1 (0.48) CYP11B1CYP11B2OGG1PTGS2ADRA2C
SCHEMBL11264698 0.89 FNTA (0.48) CYP11B1CYP11B2OGG1PTGS2ADRA2C
SCHEMBL11257995 0.88 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2ADRA2CCYP2C9
SCHEMBL11260328 0.87 OGG1 (0.47) OGG1PTGS2ADRA2CCYP2C9IDO1
SCHEMBL11266968 0.86 OGG1 (0.57) OGG1PTGS2ADRA2CCYP2C9IDO1
SCHEMBL11265341 0.83 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2CYP2C9CYP3A4
SCHEMBL11268747 0.83 OGG1 (0.54) OGG1PTGS2ADRA2CCYP2C9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358458-A BACTERICIDE, FUNGICIDES NORDMARK-WERKE GMBH (DE) 1982-11-09 US disclosed