Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259985 | 1.00 | CA12 (0.33) | CA12CA9MAPTKDM4EMEN1 | |
| SCHEMBL11280803 | 0.95 | CA12 (0.35) | CA12CA9MAPTKDM4EMEN1 | |
| SCHEMBL10618065 | 0.92 | CA12 (0.33) | CA12CA9MAPTKDM4EMEN1 | |
| SCHEMBL3877465 | 0.92 | CA12 (0.33) | CA12CA9MAPTKDM4EMEN1 | |
| SCHEMBL11268720 | 0.90 | CYP2C19 (0.34) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9333313 | 0.90 | HTR2C (0.32) | — | |
| SCHEMBL11269716 | 0.85 | HTR2C (0.41) | MAPTKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9547576 | 0.82 | — | — | |
| SCHEMBL6701609 | 0.81 | CYP2C19 (0.35) | HTT | |
| SCHEMBL10933341 | 0.71 | HTR2C (0.36) | CA12CA9MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345073-A | 7,7'-Diamino derivatives of 2,2'-spirodibenzopyranes | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| US-4316027-A | DYE INTERMEDIATES USED IN THE MANUFACTURE OF PRESSURE SENSITIVE RECORDING MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| US-4110348-A | PRESSURE SENSITIVE RECORDING | BASF AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |