Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450092 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SOAT1HSD17B10LMNAALOX15 | |
| SCHEMBL1598833 | 0.91 | ALDH1A1 (0.41) | ALDH1A1SOAT1ALOX15 | |
| SCHEMBL10595745 | 0.91 | ALDH1A1 (0.41) | ALDH1A1SOAT1ALOX15 | |
| SCHEMBL28101735 | 0.83 | ALDH1A1 (0.77) | ALDH1A1SOAT1HSD17B10LMNAALOX15 | |
| SCHEMBL9623186 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SOAT1HSD17B10LMNAALOX15 | |
| SCHEMBL1216481 | 0.81 | — | — | |
| SCHEMBL3455393 | 0.80 | CYP1A2 (0.47) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL23388854 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SOAT1HSD17B10LMNAALOX15 | |
| SCHEMBL12097090 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SOAT1HSD17B10LMNAALOX15 | |
| SCHEMBL12097092 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SOAT1HSD17B10LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296933-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2025-09-25 | — | — | US | disclosed |
| US-4362670-A | Allylation of carbon compounds | THE DOW CHEMICAL COMPANY (US) | 1982-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296933-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11B1, CYP11A1, CYP11B2 | ALDH1A1 205/4885SOAT1 327/4885HSD17B10 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.