Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119306 | 0.83 | FFAR1 (0.51) | MRGPRX4IDH1KMT2AMEN1KDM4E | |
| SCHEMBL5207539 | 0.82 | PPARG (0.51) | IDH1KMT2AALDH1A1PPARGGRM2 | |
| SCHEMBL1274836 | 0.82 | MEN1 (0.45) | PRMT5WDR77PTGDR2MRGPRX4KMT2A | |
| SCHEMBL10845520 | 0.80 | KMT2A (0.43) | MRGPRX4IDH1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4007944 | 0.79 | MRGPRX4 (0.51) | PTGDR2MRGPRX4KMT2AMEN1 | |
| SCHEMBL10963334 | 0.78 | FFAR1 (0.58) | PTGDR2MRGPRX4IDH1KMT2AMEN1 | |
| SCHEMBL1275937 | 0.78 | HTT (0.44) | MRGPRX4KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL11210510 | 0.77 | IDH1 (0.51) | IDH1KMT2AMEN1ALDH1A1GRM2 | |
| SCHEMBL6995306 | 0.77 | LMNA (0.47) | MRGPRX4IDH1KMT2AMEN1PPARG | |
| SCHEMBL9572378 | 0.77 | KMT2A (0.40) | MRGPRX4IDH1KMT2AMEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335249-A | PREEMERGENCE AND POSTEMERGENCE | ROHM AND HAAS COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4070178-A | Herbicidal diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-01-24 | — | — | US | disclosed |