Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | CTSA | P10619 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502989 | 0.82 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11264190 | 0.82 | PRMT5 (0.45) | MEN1KMT2AMRGPRX4AKR1C3AKR1C2 | |
| SCHEMBL2687361 | 0.82 | RORB (0.39) | MRGPRX4CTSAAKR1C3AKR1C2PTGDR2 | |
| SCHEMBL30836057 | 0.81 | CES2 (0.49) | MEN1KMT2ACYP1A2CYP3A4MAPT | |
| SCHEMBL1043810 | 0.81 | CES2 (0.49) | MEN1KMT2ACYP1A2CYP3A4MAPT | |
| SCHEMBL1275937 | 0.80 | HTT (0.44) | MEN1KMT2AMRGPRX4BACE1MAPT | |
| SCHEMBL1274044 | 0.78 | CTSA (0.52) | CTSAMAPT | |
| SCHEMBL812910 | 0.76 | CTSA (0.54) | CTSAMAPT | |
| SCHEMBL11432112 | 0.75 | EPHX1 (0.52) | MEN1KMT2ACYP1A2CYP3A4MAPT | |
| SCHEMBL4750069 | 0.75 | CES2 (0.46) | MEN1KMT2ACYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314025-B2 | Mixtures of mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140187776-A1 | MIXTURES OF MESOIONIC PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-8697707-B2 | Mixtures of mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-04-15 | — | — | US | disclosed |
| EP-2461685-A2 | MIXTURES OF MESOIONIC PESTICIDES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120115722-A1 | MIXTURES OF MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-10 | — | — | US | disclosed |
| WO-2011017351-A2 | MIXTURES OF MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187776-A1 | MIXTURES OF MESOIONIC PESTICIDES | DDT, C5, CBR3 | MEN1 327/4885KMT2A 3250/4885MRGPRX4 461/4885 |
| US-20120115722-A1 | MIXTURES OF MESOIONIC PESTICIDES | DDT, C5, CBR3 | MEN1 327/4885KMT2A 3250/4885MRGPRX4 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.