Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207539 | 0.94 | PPARG (0.51) | LMNAL3MBTL1KDM4EPPARGPPARA | |
| SCHEMBL6989122 | 0.89 | LMNA (0.48) | LMNAL3MBTL1SMN1; SMN2IDH1GRM2 | |
| SCHEMBL1454525 | 0.85 | L3MBTL1 (0.57) | LMNAL3MBTL1SMN1; SMN2GRM2KMT2A | |
| SCHEMBL5205507 | 0.81 | L3MBTL1 (0.50) | LMNAL3MBTL1KDM4ESMN1; SMN2IDH1 | |
| SCHEMBL10933587 | 0.81 | IDH1 (0.47) | LMNAL3MBTL1KDM4EGAAIDH1 | |
| Metacresol SCHEMBL6989813 | 0.80 | L3MBTL1 (0.52) | LMNAL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5620986 | 0.80 | PPARG (0.51) | L3MBTL1KDM4EPPARGPPARAGAA | |
| SCHEMBL11210510 | 0.80 | IDH1 (0.51) | LMNAL3MBTL1KDM4ESMN1; SMN2IDH1 | |
| SCHEMBL11223862 | 0.80 | NPSR1 (0.52) | LMNAKDM4EPPARGPPARAGAA | |
| SCHEMBL11265314 | 0.79 | L3MBTL1 (0.46) | LMNAL3MBTL1KDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |