SCHEMBL11264225

SCHEMBL11264225

CCOC(=O)Cc1ncco1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.46
TBXAS1 P24557 1/20 0.39
CA12 O43570 2/20 0.39
CA9 Q16790 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
RECQL P46063 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6972759 0.82 HSP90AB1 (0.39) SMN1; SMN2LMNAMEN1KMT2AGAA
SCHEMBL27503511 0.78 SLC6A2 (0.31)
SCHEMBL27790692 0.76 CYP3A4 (0.38) SMN1; SMN2MEN1KMT2AGAAALDH1A1
SCHEMBL4706813 0.76
SCHEMBL8041293 0.74
SCHEMBL22015495 0.73 CES1 (0.46) SMN1; SMN2MEN1KMT2AGAAMGAM
Hydrochloric Acid SCHEMBL20502167 0.73 CYP3A4 (0.35) SMN1; SMN2MEN1KMT2AGAAALDH1A1
SCHEMBL12746893 0.72 SMN1; SMN2 (0.54) SMN1; SMN2CA12CA9CA1CA2
SCHEMBL28987809 0.72 SMN1; SMN2 (0.49) SMN1; SMN2CA12CA9CA1CA2
SCHEMBL27829426 0.72 SMN1; SMN2 (0.49) SMN1; SMN2CA12CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110114354-A Condensed heterocyclic compounds or its esters with oximido and salt, garderning pesticide and its application method containing these compounds 日本农药株式会社 2019-08-09 CN disclosed
CN-109415357-A Condensed heterocyclic compounds or its esters with hydrazone group and salt, garderning pesticide and its application method containing the compound 日本农药株式会社 2019-03-01 CN disclosed
US-4365066-A ANTILIPEMIC AGENTS YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) 1982-12-21 US disclosed