Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264225 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL12343975 | 0.71 | SMN1; SMN2 (0.59) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL14907146 | 0.71 | SMN1; SMN2 (0.59) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL2142944 | 0.71 | CYP1A2 (0.42) | CA12CA1CA2CA9MAPK1 | |
| Acetic Acid SCHEMBL28987845 | 0.71 | CTSK (0.36) | KMT2AGAA | |
| Hydrochloric Acid SCHEMBL8910876 | 0.70 | CYP1A2 (0.41) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL30846050 | 0.69 | MTNR1A (0.37) | SMN1; SMN2GAARAB9AALDH1A1 | |
| SCHEMBL12746893 | 0.69 | SMN1; SMN2 (0.54) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL26384544 | 0.69 | SMN1; SMN2 (0.56) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL11608428 | 0.69 | SMN1; SMN2 (0.56) | SMN1; SMN2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835656-A | 1,3, 4-oxadiazole ethyl acetate and synthesis method thereof | 天津中医药大学 | 2022-08-02 | — | — | CN | claimed |
| CN-114835656-A | 1,3, 4-oxadiazole ethyl acetate and synthesis method thereof | 天津中医药大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114835656-A | 1,3, 4-oxadiazole ethyl acetate and synthesis method thereof | 天津中医药大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114835656-A | 1,3, 4-oxadiazole ethyl acetate and synthesis method thereof | 天津中医药大学 | 2022-08-02 | — | — | CN | disclosed |