Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737478 | 0.82 | ALDH1A1 (0.47) | CYP3A4ALDH1A1CYP1A2CYP2C19ACACB | |
| SCHEMBL27629575 | 0.78 | CYP3A4 (0.42) | CYP3A4ALDH1A1ACACBGAAL3MBTL1 | |
| SCHEMBL26181499 | 0.76 | CYP3A4 (0.31) | CYP3A4HPGD | |
| SCHEMBL11264225 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27769011 | 0.71 | KMT2A (0.37) | HTTHIF1AFAAHCES1KMT2A | |
| SCHEMBL6972759 | 0.71 | HSP90AB1 (0.39) | HTTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL724318 | 0.71 | — | — | |
| SCHEMBL34471962 | 0.70 | P2RX7 (0.49) | HTTALDH1A1HPGDL3MBTL1KMT2A | |
| SCHEMBL12530301 | 0.70 | IAPP (0.40) | FAAHCES1SLC6A2SLC6A4 | |
| SCHEMBL20509898 | 0.69 | CYP3A4 (0.35) | CYP3A4CYP1A2CYP2C19FAAHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101830894-A | Benzo[d]oxazole compounds and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2010-09-15 | — | — | CN | claimed |
| CN-101830894-B | Benzo[d]oxazole compounds and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2013-05-29 | — | — | CN | disclosed |
| CN-101830894-A | Benzo[d]oxazole compounds and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2010-09-15 | — | — | CN | disclosed |