Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 8/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | AADAC | P22760 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249084 | 0.90 | MEN1 (0.57) | HTTLMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL11254289 | 0.86 | HTT (0.52) | HTTLMNAARSMN1; SMN2MAPK1 | |
| SCHEMBL11261263 | 0.86 | MEN1 (0.43) | HTTLMNAARSMN1; SMN2MAPK1 | |
| SCHEMBL11249445 | 0.84 | HTT (0.57) | HTTARSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11252470 | 0.84 | MEN1 (0.56) | HTTLMNASMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL11253325 | 0.84 | MAPT (0.43) | HTTLMNAARSMN1; SMN2MAPK1 | |
| SCHEMBL11258189 | 0.83 | LMNA (0.46) | HTTLMNAARSMN1; SMN2MAPK1 | |
| SCHEMBL11051596 | 0.82 | KMT2A (0.55) | HTTLMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL11261746 | 0.81 | HTT (0.50) | HTTLMNAARSMN1; SMN2MAPK1 | |
| SCHEMBL11250658 | 0.81 | HTT (0.60) | HTTLMNAARSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |