Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127189 | 0.90 | CASR (0.35) | CASRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1126449 | 0.80 | MAPT (0.41) | MAPTCYP1A2CYP3A4CYP2D6LMNA | |
| SCHEMBL1127598 | 0.74 | DRD4 (0.39) | CASRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1987967 | 0.73 | MAPT (0.41) | MAPTCYP1A2CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL1993235 | 0.73 | KCNQ2 (0.36) | CASRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1126906 | 0.73 | GAA (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1989517 | 0.72 | MAPT (0.42) | MAPTDRD4LMNASMN1; SMN2 | |
| SCHEMBL1988341 | 0.72 | DRD4 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1127154 | 0.72 | LMNA (0.36) | MAPTCYP1A2CYP3A4CYP2D6LMNA | |
| SCHEMBL1127435 | 0.72 | MAPT (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |