SCHEMBL1127598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1989517	0.93	MAPT (0.42)	DRD4NPY2RMAPTGAASMN1; SMN2
	SCHEMBL1988341	0.90	DRD4 (0.38)	DRD4NPY2RPSEN1PSEN2APH1B
	SCHEMBL1993235	0.83	KCNQ2 (0.36)	DRD4NPY2RPSEN1PSEN2APH1B
	SCHEMBL1987967	0.82	MAPT (0.41)	MAPTCYP1A2CYP3A4CYP2D6ALDH1A1
	SCHEMBL1126449	0.76	MAPT (0.41)	MAPTCYP1A2CYP3A4CYP2D6ALDH1A1
	SCHEMBL1126428	0.74	CASR (0.37)	DRD4PSEN1PSEN2APH1BNCSTN
	SCHEMBL1126361	0.73	MAPT (0.41)	MAPTCYP1A2CYP3A4CYP2D6ALDH1A1
	SCHEMBL1126056	0.73	LMNA (0.42)	MAPTCYP1A2CYP3A4CYP2D6ALDH1A1
	SCHEMBL1126906	0.72	GAA (0.35)	NPY2RPSEN1PSEN2APH1BNCSTN
	SCHEMBL1127594	0.72	MAPT (0.37)	NPY2RMAPTCYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.