Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200115 | 0.83 | P2RX7 (0.41) | P2RX7TSHRKMT2ACYP2D6CYP2C19 | |
| SCHEMBL18938394 | 0.83 | P2RX7 (0.41) | P2RX7TSHRKMT2ACYP2D6CYP2C19 | |
| SCHEMBL1451694 | 0.81 | P2RX7 (0.35) | P2RX7TSHRCYP2D6HTTCYP2C19 | |
| Ethylene SCHEMBL20471720 | 0.80 | P2RX7 (0.40) | P2RX7TSHRKMT2ACYP2D6CYP2C19 | |
| SCHEMBL1451705 | 0.77 | MAPT (0.39) | P2RX7GAAHTT | |
| SCHEMBL565525 | 0.74 | HSD11B1 (0.35) | P2RX7CYP2D6CYP2C19 | |
| SCHEMBL5456663 | 0.73 | P2RX7 (0.39) | P2RX7CYP2D6CYP2C19 | |
| SCHEMBL1451420 | 0.73 | P2RX7 (0.37) | P2RX7KMT2ACYP2D6CYP2C19 | |
| SCHEMBL200228 | 0.73 | CYP2C19 (0.40) | P2RX7TSHRCYP2D6CYP2C19LMNA | |
| SCHEMBL3367328 | 0.73 | P2RX7 (0.37) | P2RX7CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344877-A | Bicyclo 4-acyloxypiperidine light stabilizers | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |