Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.85 |
| ▸ | HTT | P42858 | 4/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.85 |
| ▸ | GAA | P10253 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846139 | 0.92 | MAPK1 (1.00) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL9726804 | 0.85 | MAPT (0.82) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL11260473 | 0.85 | MAPK1 (0.65) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL5175720 | 0.84 | MAPK1 (0.77) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL7344334 | 0.84 | MAPK1 (0.64) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL10727439 | 0.84 | MAPK1 (0.81) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL11067446 | 0.83 | MAPK1 (0.64) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL3809736 | 0.83 | MAPT (0.82) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL11421508 | 0.82 | MAPK1 (0.62) | MAPK1HTTNPSR1GAAMAPT | |
| SCHEMBL11266959 | 0.82 | MAPT (0.65) | MAPK1HTTNPSR1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323691-A | Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters | ABBOTT LABORATORIES (US) | 1982-04-06 | — | — | US | disclosed |