Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | BCL9 | O00512 | 1/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264402 | 0.82 | MAPK1 (0.85) | MAPTMAPK1TDP1POLBNPSR1 | |
| SCHEMBL11266950 | 0.80 | MAPT (0.69) | MAPTMAPK1TDP1POLBNPSR1 | |
| SCHEMBL133257 | 0.80 | BCL9 (1.00) | MAPTMAPK1BCL9CTNNB1HTT | |
| SCHEMBL26111924 | 0.79 | BCL9 (0.97) | MAPTMAPK1BCL9CTNNB1HTT | |
| SCHEMBL10728358 | 0.78 | BCL9 (0.83) | MAPTMAPK1BCL9CTNNB1GAA | |
| SCHEMBL11421535 | 0.78 | MAPT (0.65) | MAPTMAPK1TDP1POLBNPSR1 | |
| SCHEMBL6846139 | 0.77 | MAPK1 (1.00) | MAPTMAPK1TDP1POLBNPSR1 | |
| SCHEMBL11067446 | 0.76 | MAPK1 (0.64) | MAPTMAPK1TDP1POLBNPSR1 | |
| SCHEMBL27475086 | 0.75 | BCL9 (0.61) | MAPTMAPK1BCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL11421508 | 0.75 | MAPK1 (0.62) | MAPTMAPK1TDP1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323691-A | Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters | ABBOTT LABORATORIES (US) | 1982-04-06 | — | — | US | disclosed |