Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267586 | 0.94 | ESR1 (0.36) | ALOX15ESR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11162900 | 0.94 | ESR1 (0.36) | ALOX15ESR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11168502 | 0.92 | ALOX15 (0.35) | ALOX15ESR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11265195 | 0.89 | ESR1 (0.36) | ALOX15ESR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11272013 | 0.80 | TTR (0.41) | LMNATBXA2RHIF1ATSHRCYP3A4 | |
| SCHEMBL11155990 | 0.79 | TTR (0.40) | LMNATBXA2RHIF1ATSHRCYP3A4 | |
| SCHEMBL11155858 | 0.79 | TTR (0.40) | LMNATBXA2RHIF1ATSHRCYP3A4 | |
| SCHEMBL11154040 | 0.77 | LMNA (0.43) | ALOX15ESR1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11264437 | 0.77 | SIGMAR1 (0.33) | ESR1TDP1LMNACYP2D6SLC6A4 | |
| SCHEMBL11154050 | 0.77 | ESR1 (0.41) | ESR1ALDH1A1SMN1; SMN2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |