Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675433 | 0.83 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL12347301 | 0.80 | KIF11 (0.53) | KIF11DNMT1 | |
| SCHEMBL5495199 | 0.79 | KIF11 (0.47) | KIF11DNMT1 | |
| SCHEMBL13177607 | 0.78 | KIF11 (0.44) | KIF11DNMT1 | |
| SCHEMBL5496858 | 0.78 | KIF11 (0.44) | KIF11DNMT1 | |
| SCHEMBL10503169 | 0.77 | KIF11 (0.42) | KIF11DNMT1 | |
| SCHEMBL342181 | 0.76 | KIF11 (0.50) | KIF11DNMT1 | |
| SCHEMBL1364085 | 0.76 | KIF11 (0.49) | KIF11 | |
| SCHEMBL11266403 | 0.75 | CYP1A2 (0.43) | KIF11 | |
| SCHEMBL11259831 | 0.75 | KIF11 (0.48) | KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0001989-A1 | Substituted mercapto acid amides, process for their preparation, pharmaceutical composition containing same and their use | MERCK & CO. INC. (US) | 1979-05-30 | — | — | EP | disclosed |