Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675433 | 0.82 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL5496858 | 0.81 | KIF11 (0.44) | KIF11DNMT1 | |
| SCHEMBL8349509 | 0.80 | KIF11 (0.50) | KIF11DNMT1 | |
| SCHEMBL16358480 | 0.79 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL10503169 | 0.79 | KIF11 (0.42) | KIF11DNMT1 | |
| SCHEMBL11264441 | 0.79 | KIF11 (0.48) | KIF11DNMT1 | |
| SCHEMBL342181 | 0.79 | KIF11 (0.50) | KIF11DNMT1CYP2C19 | |
| SCHEMBL12142024 | 0.78 | KIF11 (0.47) | KIF11 | |
| SCHEMBL15746886 | 0.77 | KIF11 (0.46) | KIF11DNMT1 | |
| SCHEMBL13555698 | 0.76 | LMNA (0.40) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975374-B1 | RADIOMETAL-BINDING PEPTIDE ANALOGUES | IMMUNOMEDICS INC (US) | 2007-12-05 | — | — | EP | disclosed |
| US-7045503-B1 | Radiometal-binding peptide analogues | IMMUNOMEDICS, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| EP-0836618-B1 | RADIOMETAL-BINDING ANALOGUES OF LEUTENIZING HORMONE RELEASING HORMONE | IMMUNOMEDICS INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-0975374-A4 | RADIOMETAL-BINDING PEPTIDE ANALOGUES | IMMUNOMEDICS INC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-RE37710-E1 | IMAGING TUMOR | IMMUNOMEDICS, INC. | 2002-05-21 | — | — | US | disclosed |
| US-6126916-A | COMPLEXING PEPTIDE WITH RADIOACTIVE MATERIAL; MEDICAL DIAGNOSIS | IMMUNOMEDICS, INC. (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0975374-A1 | RADIOMETAL-BINDING PEPTIDE ANALOGUES | Immunomedics, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5753206-A | Radiometal-binding analogues of luteinizing hormone releasing hormone | IMMUNOMEDICS, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0836618-A1 | RADIOMETAL-BINDING ANALOGUES OF LEUTENIZING HORMONE RELEASING HORMONE | Immunomedics, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1998002192-A1 | RADIOMETAL-BINDING PEPTIDE ANALOGUES | IMMUNOMEDICS, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1996040756-A1 | RADIOMETAL-BINDING ANALOGUES OF LEUTENIZING HORMONE RELEASING HORMONE | IMMUNOMEDICS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |