Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721048 | 0.89 | KDM4E (0.35) | NR4A2KDM4ELMNACYP3A4MAPK1 | |
| SCHEMBL27750582 | 0.83 | — | — | |
| SCHEMBL7128881 | 0.78 | PTGS1 (0.43) | TDP1NR4A2KDM4ELMNACYP3A4 | |
| SCHEMBL22356152 | 0.78 | KDM4E (0.44) | NR4A2KDM4ELMNACYP3A4MAPK1 | |
| SCHEMBL5492196 | 0.78 | ADORA3 (0.39) | NR4A2KDM4ELMNACYP3A4MAPK1 | |
| SCHEMBL2719464 | 0.78 | TDO2 (0.42) | NR4A2KDM4ELMNACYP3A4MAPK1 | |
| SCHEMBL48083 | 0.76 | KDM4E (0.44) | NR4A2KDM4ELMNACYP3A4MAPK1 | |
| SCHEMBL2721281 | 0.75 | NR4A2 (0.49) | NR4A2KDM4ELMNACYP3A4MAPK1 | |
| SCHEMBL15161586 | 0.74 | ABCG2 (0.41) | TDP1KDM4ELMNACYP3A4MEN1 | |
| SCHEMBL15159746 | 0.73 | ABCG2 (0.35) | TDP1KDM4ELMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061206-A1 | 6-Aminopenicillanic acid esters and their use for producing new ampicillin esters | KANEBO, LTD. (JP) | 1982-09-29 | — | — | EP | disclosed |