Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | DRD5 | P21918 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250152 | 0.99 | KCNH2 (0.62) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11270477 | 0.91 | HRH1 (0.71) | KDM4EALDH1A1MEN1KMT2AHRH1 | |
| SCHEMBL11251607 | 0.90 | HRH1 (0.71) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11257123 | 0.89 | L3MBTL1 (0.60) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11253990 | 0.88 | L3MBTL1 (0.61) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11259087 | 0.86 | KCNH2 (0.58) | KCNH2KDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11251231 | 0.86 | ALDH1A1 (0.60) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11252266 | 0.86 | ALDH1A1 (0.72) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11260259 | 0.83 | HRH3 (0.69) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11256589 | 0.83 | HRH1 (0.72) | KCNH2KDM4EALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |