Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.71 |
| ▸ | DRD1 | P21728 | 3/20 | 0.69 |
| ▸ | DRD4 | P21917 | 3/20 | 0.69 |
| ▸ | DRD5 | P21918 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251607 | 0.99 | HRH1 (0.71) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11251197 | 0.92 | HRH1 (0.77) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11256589 | 0.92 | HRH1 (0.72) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11264617 | 0.91 | KCNH2 (0.61) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11257123 | 0.90 | L3MBTL1 (0.60) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11250152 | 0.90 | KCNH2 (0.62) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11253990 | 0.88 | L3MBTL1 (0.61) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11630424 | 0.88 | HRH1 (0.92) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11250769 | 0.87 | KCNH2 (0.62) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11262935 | 0.87 | SIGMAR1 (0.61) | HRH1DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |