Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381324 | 0.89 | GAA (0.61) | GAAPOLBGFERLMNACA12 | |
| SCHEMBL28164 | 0.89 | GAA (0.61) | GAAPOLBGFERLMNACA12 | |
| SCHEMBL7761813 | 0.87 | GAA (0.50) | GAAPOLBGFERLMNACA12 | |
| SCHEMBL9460121 | 0.86 | HSD11B1 (0.59) | GAAPOLBGFERLMNAPKM | |
| SCHEMBL9635238 | 0.86 | HSD11B1 (0.65) | GAAPOLBGFERLMNAPKM | |
| SCHEMBL20723646 | 0.86 | HTR6 (0.71) | GAAPOLBGFERLMNACA12 | |
| Phenol SCHEMBL6905378 | 0.83 | HTR6 (0.62) | GAAPOLBGFERLMNACA12 | |
| SCHEMBL312518 | 0.83 | HTR6 (0.70) | GAAPOLBGFERLMNACA12 | |
| SCHEMBL7937451 | 0.83 | HTR6 (0.70) | GAAPOLBGFERLMNACA12 | |
| SCHEMBL7266402 | 0.82 | HSD11B1 (0.61) | GAAPOLBGFERPKMENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009184-B1 | BIS(4-HYDROXYPHENYLTHIO) BENZENE, ITS PREPARATION AND APPLICATION FOR THE PREPARATION OF POLYCARBONATES | Mobay Chemical Corporation (US) | 1982-06-23 | — | — | EP | disclosed |
| EP-0009184-A1 | Bis(4-hydroxyphenylthio) benzene, its preparation and application for the preparation of polycarbonates | Mobay Chemical Corporation (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0009184-A1 | Bis(4-hydroxyphenylthio) benzene, its preparation and application for the preparation of polycarbonates | Mobay Chemical Corporation (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4188489-A | Process for the production of 3-substituted amino-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |