Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.56 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664197 | 0.94 | ALDH1A1 (0.65) | ADORA3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL10830286 | 0.85 | PDE1C (0.70) | ADORA3KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL27273792 | 0.79 | TSHR (0.54) | ADORA3ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL11262327 | 0.78 | KMT2A (0.60) | ADORA3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL3004824 | 0.77 | PDE1C (0.69) | ADORA3KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16323913 | 0.76 | ALDH1A1 (0.81) | KDM4EALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL5766699 | 0.76 | SMN1; SMN2 (0.65) | ADORA3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL9034198 | 0.76 | CYP2C9 (0.69) | ADORA3KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL9032624 | 0.76 | CACNA1C (0.66) | ADORA3MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL7687629 | 0.76 | ADORA3 (0.75) | ADORA3KDM4ELMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317768-A | A PHENYL DIESTER OF 3,5-DICARBOXY-1,4-DIHYDROPYRIDINE | LABAZ (FR) | 1982-03-02 | — | — | US | disclosed |
| US-4239893-A | STABILIZERS FOR VINYL RESINS | LABAZ (FR) | 1980-12-16 | — | — | US | disclosed |