Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938124 | 0.81 | CYP19A1 (0.44) | CYP19A1TSHRALDH1A1ALOX15MEN1 | |
| SCHEMBL11268013 | 0.81 | CYP19A1 (0.39) | CYP19A1ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL11261538 | 0.79 | POLB (0.40) | CYP19A1ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL11628406 | 0.77 | CYP19A1 (0.41) | CYP19A1TSHRALDH1A1ALOX15CTSL | |
| SCHEMBL11143559 | 0.74 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6767572 | 0.74 | KDM4E (0.39) | TSHRALDH1A1SMN1; SMN2KDM4EGLA | |
| SCHEMBL11261869 | 0.73 | CYP19A1 (0.41) | CYP19A1ALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL28680178 | 0.73 | CYP19A1 (0.49) | CYP19A1TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL11685815 | 0.72 | CYP19A1 (0.71) | CYP19A1SMN1; SMN2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13505959 | 0.70 | CYP19A1 (0.46) | CYP19A1ALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |