Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263713 | 0.89 | CYP19A1 (0.37) | CYP19A1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3293497 | 0.75 | CYP19A1 (0.47) | CYP19A1KDM4ECYP1A2CYP2C19HSP90AA1 | |
| SCHEMBL11249250 | 0.74 | KDM4E (0.39) | CYP19A1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL11264781 | 0.73 | CYP19A1 (0.44) | CYP19A1KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11256467 | 0.73 | ADORA3 (0.41) | CYP19A1KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL28526063 | 0.72 | HSP90AA1 (0.35) | CYP19A1KDM4EHSP90AA1ALOX15 | |
| SCHEMBL28453438 | 0.71 | CYP19A1 (0.44) | CYP19A1KDM4EALDH1A1HSP90AA1ALOX15 | |
| SCHEMBL11266079 | 0.71 | CYP19A1 (0.34) | CYP19A1HSP90AA1 | |
| SCHEMBL29526853 | 0.70 | TRPV4 (0.44) | CYP19A1KDM4EALDH1A1HSP90AA1ALOX15 | |
| SCHEMBL631338 | 0.70 | TRPV4 (0.44) | CYP19A1KDM4EALDH1A1HSP90AA1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |