Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264781 | 0.79 | CYP19A1 (0.44) | ALDH1A1CYP19A1KMT2AMEN1CYP2C19 | |
| SCHEMBL11268013 | 0.76 | CYP19A1 (0.39) | POLBRAB9AMAPTALDH1A1CYP19A1 | |
| SCHEMBL4797038 | 0.74 | CYP1A2 (0.46) | POLBRAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL10419886 | 0.73 | HSPB1 (0.49) | POLBRAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL10420766 | 0.73 | ACHE (0.58) | POLBRAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL11141195 | 0.68 | MAPT (0.45) | RAB9AMAPTALDH1A1CYP19A1KMT2A | |
| SCHEMBL11766003 | 0.68 | ALDH1A1 (0.49) | POLBMAPTALDH1A1CYP19A1KMT2A | |
| SCHEMBL9455477 | 0.67 | MAPT (0.45) | RAB9AMAPTALDH1A1CYP19A1KMT2A | |
| SCHEMBL11807485 | 0.66 | CYP2C19 (0.56) | RAB9AMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11249250 | 0.65 | KDM4E (0.39) | POLBRAB9AMAPTALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |