Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264781 | 0.81 | CYP19A1 (0.44) | CYP19A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL11628406 | 0.81 | CYP19A1 (0.41) | CYP19A1ALDH1A1CTSLALOX15TSHR | |
| SCHEMBL11171434 | 0.79 | SMN1; SMN2 (0.47) | CYP19A1MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28680178 | 0.77 | CYP19A1 (0.49) | CYP19A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL11147179 | 0.76 | KCNA5 (0.47) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11685815 | 0.76 | CYP19A1 (0.71) | CYP19A1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13505959 | 0.74 | CYP19A1 (0.46) | CYP19A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL11153380 | 0.72 | KIF11 (0.43) | MEN1ALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL11257745 | 0.72 | ALDH1A1 (0.40) | CYP19A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL1444134 | 0.71 | ATM (0.45) | ALDH1A1CYP3A4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484787-A | Heterocyclicacetonitriles and fungicidal use | ROHM AND HAAS COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-5397793-A | Heterocyclicacetonitriles and fungicidal use | ROHM AND HAAS COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0451948-B1 | Heterocyclicacetonitriles and their fungicidal use | ROHM & HAAS (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0451948-A1 | Heterocyclicacetonitriles and their fungicidal use | ROHM AND HAAS COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| US-4398942-A | PREEMERGENCE HERBICIDES | ROHM AND HAAS COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |