Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272367 | 0.91 | MEN1 (0.33) | — | |
| SCHEMBL11276954 | 0.86 | IL1B (0.35) | KDM4EARVDR | |
| SCHEMBL11264839 | 0.84 | NR1H2 (0.35) | AR | |
| Hydrochloric Acid SCHEMBL11266399 | 0.83 | ACHE (0.30) | ARVDR | |
| SCHEMBL11267067 | 0.81 | KMT2A (0.41) | KDM4E | |
| SCHEMBL11267621 | 0.81 | HTT (0.44) | — | |
| SCHEMBL11261899 | 0.79 | TACR1 (0.32) | KDM4EVDR | |
| SCHEMBL11266630 | 0.77 | ALDH1A1 (0.38) | KDM4EVDR | |
| SCHEMBL11624160 | 0.76 | MEN1 (0.35) | — | |
| SCHEMBL11272364 | 0.75 | NR1H2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |