Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262225 | 0.92 | CYP11B1 (0.58) | CYP11B1CYP11B2HMOX2CYP19A1 | |
| SCHEMBL11256237 | 0.86 | TBXAS1 (0.43) | CYP11B1CYP11B2HMOX2 | |
| SCHEMBL11262725 | 0.85 | HMOX2 (0.50) | HMOX2CYP19A1 | |
| SCHEMBL8804388 | 0.81 | TBXAS1 (0.59) | HMOX2 | |
| Hydrochloric Acid SCHEMBL9996084 | 0.80 | TBXAS1 (0.61) | HMOX2 | |
| SCHEMBL11260275 | 0.80 | HMOX2 (0.53) | CYP11B1CYP11B2HMOX2CYP19A1 | |
| SCHEMBL11247258 | 0.80 | TBXAS1 (0.44) | CYP11B1CYP11B2HMOX2CYP19A1 | |
| SCHEMBL11265758 | 0.80 | CYP11B1 (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL8803506 | 0.79 | TBXAS1 (0.56) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL22418800 | 0.77 | TAAR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |