Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264399 | 0.92 | CYP11B1 (0.58) | CYP11B1CYP11B2TBXAS1MEN1KMT2A | |
| SCHEMBL11261839 | 0.85 | KDM4E (0.50) | TBXAS1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL11272692 | 0.85 | TBXAS1 (0.51) | TBXAS1LMNAMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL11243099 | 0.81 | TBXAS1 (0.59) | CYP11B1CYP11B2TBXAS1POLBSMN1; SMN2 | |
| SCHEMBL11259586 | 0.80 | TBXAS1 (0.51) | CYP11B1CYP11B2TBXAS1ALDH1A1KDM4E | |
| SCHEMBL11264962 | 0.80 | CYP11B1 (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL11243829 | 0.79 | CYP19A1 (0.54) | CYP11B1CYP11B2TBXAS1ALDH1A1KDM4E | |
| SCHEMBL11261485 | 0.79 | TBXAS1 (0.60) | CYP11B1CYP11B2TBXAS1MEN1KMT2A | |
| SCHEMBL11245721 | 0.77 | POLB (0.48) | CYP11B1CYP11B2TBXAS1MEN1KMT2A | |
| SCHEMBL11250165 | 0.76 | ALDH1A1 (0.49) | TBXAS1LMNAMAPK1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |