Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 12/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.43 |
| ▸ | NPC1 | O15118 | 10/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264138 | 0.93 | RAB9A (0.48) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11255071 | 0.92 | RAB9A (0.47) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11259059 | 0.91 | MAPT (0.44) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11256671 | 0.82 | RAB9A (0.49) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11262720 | 0.80 | SMN1; SMN2 (0.52) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11257864 | 0.79 | CASP2 (0.56) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4509401 | 0.79 | RAB9A (0.50) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11264970 | 0.77 | RAB9A (0.44) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4493348 | 0.77 | CASP2 (0.55) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11254531 | 0.77 | MAPK1 (0.49) | ALDH1A1HSD17B10RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |