Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.52 |
| ▸ | RAB9A | P51151 | 11/20 | 0.52 |
| ▸ | NPC1 | O15118 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11255071 | 0.85 | RAB9A (0.47) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11256671 | 0.83 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11264975 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4509401 | 0.79 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4493348 | 0.78 | CASP2 (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11254531 | 0.78 | MAPK1 (0.49) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11259059 | 0.77 | MAPT (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11256200 | 0.76 | TERT (0.52) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11253925 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL11255668 | 0.73 | RAB9A (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |