Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270277 | 1.00 | LMNA (0.56) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL11271864 | 0.95 | LMNA (0.52) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL11268901 | 0.88 | LMNA (0.72) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL4731655 | 0.88 | LMNA (0.72) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL11266263 | 0.87 | LMNA (0.58) | LMNAMAPTABCB11MAPK1KCNA3 | |
| SCHEMBL11275748 | 0.87 | LMNA (0.58) | LMNAMAPTABCB11MAPK1KCNA3 | |
| SCHEMBL11268538 | 0.87 | LMNA (0.58) | LMNAMAPTABCB11MAPK1KCNA3 | |
| SCHEMBL11268263 | 0.87 | LMNA (0.58) | LMNAMAPTABCB11MAPK1KCNA3 | |
| SCHEMBL11273796 | 0.87 | ABCB11 (0.53) | LMNAMAPTABCB11MAPK1NAAA | |
| SCHEMBL11267391 | 0.86 | LMNA (0.61) | LMNAMAPTABCB11MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |