Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270277 | 0.95 | LMNA (0.56) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL11265060 | 0.95 | LMNA (0.56) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL11272380 | 0.89 | LMNA (0.54) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11264433 | 0.87 | LMNA (0.68) | LMNAMAPTABCB11MAPK1OPRM1 | |
| SCHEMBL11265171 | 0.86 | LMNA (0.54) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11276195 | 0.86 | LMNA (0.57) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11270402 | 0.85 | LMNA (0.48) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11277709 | 0.84 | LMNA (0.67) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11269898 | 0.83 | LMNA (0.56) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11263317 | 0.82 | ABCB11 (0.65) | LMNAMAPTABCB11MAPK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |