Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138432 | 0.85 | NPY2R (0.54) | HPGDGAAALDH1A1ADRB2NPY2R | |
| SCHEMBL11261219 | 0.75 | ALDH1A1 (0.37) | HPGDGAAALDH1A1ADRB2NPY2R | |
| SCHEMBL30957409 | 0.74 | NPY2R (0.53) | ALDH1A1NPY2RCYSLTR2CYSLTR1RAB9A | |
| SCHEMBL11260170 | 0.74 | ALDH1A1 (0.41) | ALDH1A1NPY2RS1PR1POLB | |
| SCHEMBL11257623 | 0.73 | HDAC3 (0.45) | ALDH1A1MAPTSMN1; SMN2CYSLTR2CYSLTR1 | |
| SCHEMBL30957337 | 0.73 | NPC1 (0.50) | ALDH1A1NPY2RCYSLTR2CYSLTR1RAB9A | |
| SCHEMBL30957315 | 0.73 | NPC1 (0.50) | ALDH1A1NPY2RCYSLTR2CYSLTR1RAB9A | |
| SCHEMBL11329851 | 0.72 | ADRA2C (0.46) | ALDH1A1MAPTSMN1; SMN2L3MBTL1LTB4R2 | |
| SCHEMBL11255842 | 0.71 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11851073 | 0.71 | ALDH1A1 (0.46) | HPGDGAAALDH1A1ADRB2NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |
| WO-1979000586-A1 | W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1979-08-23 | — | — | WO | disclosed |