Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503409 | 0.86 | S1PR1 (0.35) | ALDH1A1POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL11503412 | 0.85 | S1PR1 (0.37) | ALDH1A1HDAC3HDAC1HDAC2MAPK14 | |
| SCHEMBL11263791 | 0.85 | GPBAR1 (0.48) | ALDH1A1OPRM1OPRL1TBXA2RTBXAS1 | |
| SCHEMBL11267185 | 0.82 | GPBAR1 (0.48) | ALDH1A1OPRM1OPRL1TBXA2RTBXAS1 | |
| SCHEMBL11268722 | 0.81 | GPBAR1 (0.47) | ALDH1A1OPRM1OPRL1TBXA2RTBXAS1 | |
| SCHEMBL11337926 | 0.78 | ALDH1A1 (0.48) | ALDH1A1OPRM1OPRL1TBXA2RTBXAS1 | |
| SCHEMBL11326794 | 0.78 | CNR2 (0.45) | TBXA2RTBXAS1HDAC11HDAC8HDAC6 | |
| SCHEMBL11503411 | 0.77 | CCR2 (0.35) | HDAC3HDAC1HDAC2HDAC11HDAC8 | |
| SCHEMBL11265074 | 0.74 | HPGD (0.53) | ALDH1A1POLBNPY2RS1PR1 | |
| SCHEMBL11305431 | 0.73 | RXRA (0.47) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |