Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.51 |
| ▸ | TUBB | P07437 | 8/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265201 | 0.90 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19191488 | 0.86 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9860002 | 0.80 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14519982 | 0.80 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Parbendazole SCHEMBL259455 | 0.78 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Parbendazole SCHEMBL29409286 | 0.78 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17702654 | 0.78 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8083834 | 0.77 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3500724 | 0.77 | ATP4A (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11120640 | 0.76 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |