Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 16/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253134 | 0.88 | KDM4E (0.33) | PTGES | |
| SCHEMBL11251581 | 0.87 | KDM4E (0.32) | PTGES | |
| SCHEMBL11262332 | 0.86 | ALDH1A1 (0.32) | PTGESPDE2A | |
| SCHEMBL11248479 | 0.85 | SOS1 (0.36) | PTGES | |
| SCHEMBL11255098 | 0.84 | THRB (0.32) | PTGESPDE2A | |
| SCHEMBL11254579 | 0.84 | ALDH1A1 (0.31) | PTGES | |
| SCHEMBL11262181 | 0.84 | ALDH1A1 (0.32) | PTGES | |
| SCHEMBL11246820 | 0.83 | KDM4E (0.30) | — | |
| SCHEMBL11260537 | 0.82 | GPR119 (0.33) | — | |
| SCHEMBL11244578 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |