Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805675 | 0.79 | POLB (0.47) | POLBALDH1A1PBRM1TP53TRPM8 | |
| SCHEMBL11674241 | 0.78 | POLB (0.46) | POLBALDH1A1PBRM1TP53TRPM8 | |
| SCHEMBL11265368 | 0.76 | POLB (0.45) | POLBALDH1A1PBRM1TP53TRPM8 | |
| SCHEMBL28904678 | 0.75 | POLB (0.44) | POLBALDH1A1PBRM1TP53TRPM8 | |
| SCHEMBL11256252 | 0.74 | KDM4E (0.65) | POLBALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11264425 | 0.74 | KDM4E (0.55) | POLBALDH1A1KDM4EHPGDTRPM8 | |
| SCHEMBL11003485 | 0.72 | ALDH1A1 (0.52) | POLBALDH1A1KDM4EHPGDTRPM8 | |
| SCHEMBL11262660 | 0.72 | ALDH1A1 (0.47) | POLBALDH1A1TRPM8FEN1MAPT | |
| SCHEMBL28299711 | 0.72 | KDM4E (0.62) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL133668 | 0.71 | KDM4E (0.67) | POLBALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365082-A | CATALYTIC OXIDATION, ESTERIFICATION | INSTITUT FRANCAIS DU PETROLE (FR) | 1982-12-21 | — | — | US | claimed |
| US-4365082-A | CATALYTIC OXIDATION, ESTERIFICATION | INSTITUT FRANCAIS DU PETROLE (FR) | 1982-12-21 | — | — | US | disclosed |