SCHEMBL11265368

SCHEMBL11265368

O=C(c1c(Cl)cccc1Cl)N([O-])c1ccccc1.O=C(c1c(Cl)cccc1Cl)N([O-])c1ccccc1.[Pd+2]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
ALDH1A1 P00352 2/20 0.44
FEN1 P39748 1/20 0.43
TP53 P04637 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
PBRM1 Q86U86 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
FABP3 P05413 1/20 0.36
FABP4 P15090 1/20 0.36
TSHR P16473 1/20 0.36
AKR1B1 P15121 1/20 0.36
GPBAR1 Q8TDU6 1/20 0.36
MAPT P10636 1/20 0.36
PTK2B Q14289 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9805675 0.78 POLB (0.47) POLBALDH1A1FEN1TP53TRPM8
SCHEMBL11674241 0.76 POLB (0.46) POLBALDH1A1FEN1TP53TRPM8
SCHEMBL11265372 0.76 POLB (0.46) POLBALDH1A1FEN1TP53TRPM8
SCHEMBL11256256 0.75 L3MBTL1 (0.48) ALDH1A1NPSR1TSHRKMT2ACES2
SCHEMBL11264423 0.75 CA12 (0.53) POLBALDH1A1TRPM8MEN1KMT2A
SCHEMBL28904678 0.74 POLB (0.44) POLBALDH1A1FEN1TP53TRPM8
SCHEMBL11262658 0.71 ALDH1A1 (0.44) POLBALDH1A1FEN1TRPM8NPSR1
SCHEMBL11270840 0.71 L3MBTL1 (0.48) ALDH1A1NPSR1TSHRKMT2ACES2
SCHEMBL11681600 0.71 L3MBTL1 (0.48) ALDH1A1FEN1NPSR1TSHRKMT2A
Acetic Acid SCHEMBL11258107 0.69 RAB9A (0.43) ALDH1A1NPSR1KMT2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4365082-A CATALYTIC OXIDATION, ESTERIFICATION INSTITUT FRANCAIS DU PETROLE (FR) 1982-12-21 US claimed
US-4365082-A CATALYTIC OXIDATION, ESTERIFICATION INSTITUT FRANCAIS DU PETROLE (FR) 1982-12-21 US disclosed