Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726366 | 0.81 | PLA2G10 (0.56) | KMT2AMEN1L3MBTL1MMP1MMP3 | |
| SCHEMBL11265232 | 0.76 | PLA2G10 (0.48) | KMT2AMEN1L3MBTL1MMP1MMP3 | |
| SCHEMBL11271882 | 0.76 | PLA2G10 (0.53) | L3MBTL1MMP1MMP3MMP9CNR2 | |
| SCHEMBL8726569 | 0.75 | HDAC8 (0.46) | SMN1; SMN2KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL11259620 | 0.74 | HSD17B10 (0.51) | SMN1; SMN2KMT2AMEN1MAPTMMP1 | |
| SCHEMBL11263507 | 0.73 | LMNA (0.47) | KMT2AMEN1L3MBTL1TNFMMP1 | |
| SCHEMBL11267916 | 0.73 | CAPN1 (0.48) | L3MBTL1MAPTMMP1MMP3MMP9 | |
| SCHEMBL11256499 | 0.73 | NPSR1 (0.49) | L3MBTL1TNFMMP1MMP3MMP9 | |
| SCHEMBL11263043 | 0.73 | LMNA (0.39) | SMN1; SMN2KMT2AMEN1MAPTTNF | |
| SCHEMBL11264004 | 0.72 | MMP1 (0.40) | SMN1; SMN2KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |