Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264631 | 0.89 | ADRA2C (0.39) | CYP19A1ADRA2C | |
| SCHEMBL11256509 | 0.89 | LMNA (0.38) | LMNAMAPTUSP2MAPK1CYP19A1 | |
| SCHEMBL11255287 | 0.88 | USP2 (0.37) | LMNAUSP2MAPK1CYP19A1ALOX15 | |
| SCHEMBL11252662 | 0.87 | LMNA (0.35) | LMNAMAPTUSP2MAPK1ALOX15 | |
| SCHEMBL11260943 | 0.84 | ADRA2C (0.38) | CYP19A1ADRA2C | |
| SCHEMBL11258066 | 0.84 | USP2 (0.36) | LMNAUSP2MAPK1CYP19A1ALOX15 | |
| SCHEMBL11270296 | 0.82 | LMNA (0.42) | LMNAMAPTUSP2MAPK1ALOX15 | |
| SCHEMBL11264094 | 0.82 | ADRA2C (0.38) | LMNAUSP2MAPK1CYP19A1ALOX15 | |
| SCHEMBL11270723 | 0.81 | CYP2A6 (0.51) | CYP19A1 | |
| SCHEMBL11256067 | 0.81 | CYP2C9 (0.42) | LMNAMAPTUSP2MAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |