SCHEMBL11260943

SCHEMBL11260943

Clc1cc(Cl)c(CCC2(Cn3ccnc3)SCCCS2)c(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.38
CYP19A1 P11511 1/20 0.37
HMOX1 P09601 2/20 0.36
OGG1 O15527 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11264631 0.95 ADRA2C (0.39) ADRA2CCYP19A1HMOX1
SCHEMBL11264094 0.88 ADRA2C (0.38) ADRA2CCYP19A1HMOX1
SCHEMBL11256513 0.88 ADRA2C (0.39) ADRA2CCYP19A1OGG1
SCHEMBL11255399 0.86 HMOX1 (0.35) HMOX1
SCHEMBL11265408 0.84 LMNA (0.38) ADRA2CCYP19A1
SCHEMBL11261268 0.83 ADRA2C (0.40) ADRA2CCYP19A1
SCHEMBL11256591 0.82 HMOX1 (0.54) CYP19A1HMOX1
SCHEMBL11269757 0.82 HMOX1 (0.40) ADRA2CCYP19A1HMOX1
SCHEMBL11261042 0.81 HMOX1 (0.37) HMOX1
SCHEMBL11263905 0.81 ADRA2C (0.41) ADRA2CCYP19A1OGG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359475-A SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS SYNTEX (U.S.A.) INC. (US) 1982-11-16 US disclosed