Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 5/20 | 0.41 |
| ▸ | FNTB | P49356 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.41 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251801 | 0.90 | HMOX1 (0.40) | ADRA2CFNTAFNTBCYP2C9CYP17A1 | |
| SCHEMBL11268945 | 0.89 | ADRA2C (0.42) | ADRA2CFNTAFNTBCYP2C9CYP17A1 | |
| SCHEMBL11263546 | 0.88 | MAPT (0.39) | FNTAFNTBCYP2C9CYP17A1PGR | |
| SCHEMBL11257609 | 0.88 | FNTA (0.39) | ADRA2CFNTAFNTBCYP2C9CYP17A1 | |
| SCHEMBL11265152 | 0.87 | CYP19A1 (0.39) | FNTAFNTBCYP17A1CYP3A4CYP2D6 | |
| SCHEMBL11265549 | 0.86 | ADRA2C (0.41) | ADRA2CFNTAFNTBCYP2C9CYP17A1 | |
| SCHEMBL11254200 | 0.86 | ADRA2C (0.46) | ADRA2CFNTAFNTBCYP2C9CYP17A1 | |
| SCHEMBL11257432 | 0.85 | CYP2A6 (0.47) | CYP19A1CYP11B1 | |
| SCHEMBL11252816 | 0.82 | FNTA (0.38) | ADRA2CFNTAFNTBCYP2C9CYP17A1 | |
| SCHEMBL11259885 | 0.80 | CYP2C9 (0.40) | ADRA2CFNTAFNTBCYP2C9CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |