SCHEMBL11265609

SCHEMBL11265609

NS(=O)(=O)N(c1ccccc1)c1ncccn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
PKM P14618 1/20 0.41
ESR1 P03372 1/20 0.39
CA2 P00918 8/20 0.38
CA9 Q16790 6/20 0.37
CA1 P00915 5/20 0.37
CA12 O43570 2/20 0.37
CA5A P35218 2/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37
PLA2G7 Q13093 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
KMT2A Q03164 1/20 0.35
MAPK1 P28482 1/20 0.34
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132005 0.83 PKM (0.50) ALDH1A1PKMESR1CA2CA9
SCHEMBL10875052 0.73 TDP1 (0.56) ALDH1A1PKMESR1CA2CA9
SCHEMBL129629 0.70 PKM (0.56) ALDH1A1PKMESR1CA2CA9
SCHEMBL27532903 0.69 KCNN4 (0.38) ALDH1A1PKMESR1CA2CA9
SCHEMBL2542150 0.69 CA2 (0.46) ALDH1A1PKMESR1CA2CA9
SCHEMBL7567279 0.68 MCL1 (0.41) ALDH1A1PKMESR1CA2CA9
SCHEMBL27488629 0.67 ALDH1A1 (0.35) ALDH1A1PKMESR1
Potassium Ion SCHEMBL29243064 0.67 PKM (0.54) ALDH1A1PKMESR1CA2CA9
SCHEMBL378350 0.67 PKM (0.54) ALDH1A1PKMESR1CA2CA9
SCHEMBL415687 0.67 PKM (0.54) ALDH1A1PKMESR1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053693-A1 Penicillins, their salts, process for their preparation and pharmaceutical compositions containing them Dr. Karl Thomae GmbH (DE) 1982-06-16 EP disclosed