Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918928 | 0.82 | PDE2A (0.47) | PDE7APDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL11659188 | 0.80 | RAB9A (0.44) | PDE7APDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL11592154 | 0.78 | MEN1 (0.55) | PDE7ANR1H2ALDH1A1MEN1KMT2A | |
| SCHEMBL9503600 | 0.77 | MAPK1 (0.41) | PDE7APDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL6251649 | 0.77 | KIF11 (0.64) | KIF11NR1H2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10615934 | 0.76 | PDE7A (0.44) | PDE7APDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL11766283 | 0.76 | MAPT (0.49) | ALDH1A1KMT2AMAPT | |
| SCHEMBL11253450 | 0.75 | MAPT (0.59) | PDE7AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11761622 | 0.74 | MEN1 (0.60) | PDE7ANR1H2ALDH1A1MEN1KMT2A | |
| SCHEMBL10948498 | 0.74 | PPARA (0.46) | PDE2APKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335249-A | PREEMERGENCE AND POSTEMERGENCE | ROHM AND HAAS COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4178169-A | Diphenyl sulfide, sulfoxide and sulfone plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4070178-A | Herbicidal diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-01-24 | — | — | US | disclosed |