Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27875473 | 0.78 | TRPA1 (0.42) | MAPK1TDP1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11265653 | 0.77 | PDE7A (0.45) | MAPK1PDE7ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28918928 | 0.75 | PDE2A (0.47) | PDE7ASLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL7531828 | 0.75 | MAPK1 (0.41) | MAPK1TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL160983 | 0.74 | CYP3A4 (0.50) | MAPK1TDP1CYP3A4TSHRALDH1A1 | |
| SCHEMBL11659188 | 0.73 | RAB9A (0.44) | TDP1PDE7AMEN1KMT2APDE2A | |
| SCHEMBL11761347 | 0.73 | FFAR1 (0.54) | MAPK1TDP1SLC6A4MEN1KMT2A | |
| SCHEMBL29648890 | 0.71 | PDE2A (0.41) | MAPK1TDP1MEN1KMT2APDE2A | |
| SCHEMBL162605 | 0.71 | PDE2A (0.41) | MAPK1TDP1MEN1KMT2APDE2A | |
| SCHEMBL2789021 | 0.71 | MAPK1 (0.56) | MAPK1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318882-B1 | (THIO)BENZOYL UREAS, FUNCTIONAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS AND PESTICIDAL USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | disclosed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0318882-A2 | (Thio)benzoyl ureas, functional derivatives, process for their preparation, compositions and pesticidal use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-07 | — | — | EP | disclosed |