Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060988 | 0.86 | NISCH (0.54) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| Tymazoline SCHEMBL250491 | 0.81 | NISCH (0.70) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL11256297 | 0.81 | ADRA1A (0.58) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| Tymazoline SCHEMBL29387735 | 0.81 | NISCH (0.70) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| Cilutazoline SCHEMBL2108875 | 0.80 | NISCH (0.68) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| Tymazoline SCHEMBL4415590 | 0.80 | NISCH (0.68) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL3163294 | 0.80 | WDR5 (0.57) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL3169242 | 0.80 | NISCH (0.68) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL11265808 | 0.78 | NISCH (0.60) | NISCHADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL3170332 | 0.77 | NISCH (0.61) | NISCHADRA1AADRA1DADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343809-A | ANTIANEMIA | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| US-4343809-A | ANTIANEMIA | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |