Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823877 | 0.84 | TYR (0.42) | TYRTRIM24TRIM33ALDH1A1MAPT | |
| SCHEMBL30665426 | 0.83 | ALDH1A1 (0.47) | TYRTRIM24TRIM33ALDH1A1MAPT | |
| SCHEMBL9189739 | 0.83 | ALDH1A1 (0.47) | TYRTRIM24TRIM33ALDH1A1MAPT | |
| SCHEMBL31696766 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EKMT2ALMNA | |
| SCHEMBL9730719 | 0.81 | TDP1 (0.48) | ALDH1A1MAPTKDM4EKMT2ALMNA | |
| SCHEMBL17221903 | 0.81 | MAPT (0.42) | TYRTRIM24TRIM33ALDH1A1MAPT | |
| SCHEMBL7064653 | 0.81 | ALDH1A1 (0.51) | TYRTRIM24TRIM33ALDH1A1MAPT | |
| SCHEMBL11697271 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EKMT2ALMNA | |
| SCHEMBL10333910 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EKMT2ALMNA | |
| SCHEMBL8378029 | 0.80 | SLC16A3 (0.49) | TYRTRIM24TRIM33ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345073-A | 7,7'-Diamino derivatives of 2,2'-spirodibenzopyranes | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| US-4316027-A | DYE INTERMEDIATES USED IN THE MANUFACTURE OF PRESSURE SENSITIVE RECORDING MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| US-4110348-A | PRESSURE SENSITIVE RECORDING | BASF AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |