Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902021 | 0.83 | CTSL (0.44) | ABCB1LMNAMIFLTA4HESR1 | |
| SCHEMBL11267790 | 0.82 | ABCB1 (0.37) | ABCB1NPC1RAB9AF2PLAU | |
| SCHEMBL7381780 | 0.81 | ABCB1 (0.58) | ABCB1NPC1RAB9AF2PLAU | |
| SCHEMBL17459630 | 0.79 | ESRRG (0.48) | LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22804098 | 0.75 | ALDH1A1 (0.46) | ABCB1LMNAMIFESR1ESR2 | |
| SCHEMBL22804079 | 0.75 | ALDH1A1 (0.46) | ABCB1LMNAMIFESR1ESR2 | |
| SCHEMBL1937057 | 0.74 | ABCB1 (0.46) | ABCB1LTA4H | |
| SCHEMBL9330125 | 0.74 | ABCB1 (0.47) | ABCB1LTA4HEPOR | |
| SCHEMBL6904576 | 0.74 | ABCB1 (0.47) | ABCB1LTA4HEPOR | |
| SCHEMBL7281578 | 0.74 | EPOR (0.54) | NPC1RAB9AF2PLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |